Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
05/04/2022	Do long-term oral antibiotics for acne contribute to antibiotic treatment failure?
04/04/2022	Risk of hospitalised Influenza, England, 2011/12-2020/21 influenza seasons
01/04/2022	Identification and validation of novel and overlapping phenotypes in Asthma, Bronchiectasis and Chronic obstructive pulmonary disease using cluster analysis.
01/04/2022	Mortality and long-term health conditions associated with adverse childhood experiences: a birth cohort study
31/03/2022	Risk of herpes zoster and Bell's palsy after COVID-19 vaccination: a self-controlled case series and nested case-control study.
31/03/2022	An observational retrospective cohort study describing the changing epidemiology of asthma, interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD) in England over 15 years
24/03/2022	Mental health contact and psychotropic medication for children and young people, in primary and secondary care
24/03/2022	Describing the events and timeframes of patient pathways of four major respiratory diseases, from presentation of symptoms to diagnosis and first treatment
23/03/2022	Drospirenone-containing oral contraceptives and impact of safety advisors on prescribing in the United Kingdom: A drug utilization study with interrupted time series analysis
23/03/2022	Healthcare Resource Utilisation and Associated Costs in Patients with COVID-19 in England: A Retrospective Cohort Study
21/03/2022	TO CHARACTERISE THE HEALTH ECONOMIC IMPACT OF SURGICAL SITE INFECTIONS IN THE UK
18/03/2022	Incidence of diabetes foot ulcer disease and its association with morbidity and mortality in persons with diabetes: United Kingdom Clinical Practice Research Datalink Cohort Study.
18/03/2022	Characterizing long COVID patients across pre-existing physical and mental health conditions: Risk profiling using Electronic Health Records in the United Kingdom
18/03/2022	The impact of COVID-19 pandemic on health care service provision for patients with newly diagnosed cancer
16/03/2022	Medication use in pregnancy and pregnancy outcomes in women with chronic inflammatory disease
14/03/2022	Combining pharmacokinetics and real-world data to improve understanding of the dose-exposure-response relationship of hormonal contraceptives
14/03/2022	Psychiatric diagnoses and self-harm episodes among children and young people in UK primary care records before and during the COVID-19 pandemic: a population-based cohort study
14/03/2022	Investigating disruptions in primary care as a result of the COVID-19 pandemic and the introduction of national lockdowns
09/03/2022	The development and internal validation of population clusters for multiple long-term conditions using artificial intelligence approaches
09/03/2022	Utilization of Low-Dose Aspirin during Pregnancy and Impact of National Institute for Health and Care Excellence Guidelines on Prescription Trends