Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
07/09/2020	The care home residency population in the United Kingdom: osteoporosis-related characteristics, outcomes, and patterns of care – a descriptive study
04/09/2020	Mapping the prevalence of Chronic Venous Disease in England
01/09/2020	Long-acting insulin analogues and the risk of diabetic retinopathy, neuropathy, and nephropathy in type 2 diabetes patients.
01/09/2020	Comparing the Estimated Risk of Hip Fracture Among Subjects Exposed to Tramadol as Compared to Subjects Exposed to Codeine
28/08/2020	An assessment of patient characteristics and treatment patterns among ASCVD patients with hypercholesterolemia, ASCVD-risk equivalent patients with hypercholesterolemia and FH patients
28/08/2020	Development and validation of a risk stratification tool for patients with acute myocardial infarction (AMI) in UK primary care
28/08/2020	Improving the definition of recurrent UTI and understanding patient factors associated with greater frequency of recurrence
26/08/2020	Understanding the health of transgender people: A population-based cross-sectional and linked cohort study
24/08/2020	The value of additional risk factors in addition to current prediction rules to better predict 10-year cardiovascular risk
21/08/2020	Multimorbidity and pregnancy: epidemiology, clusters, prescriptions, and outcomes
21/08/2020	Is chronic obstructive pulmonary disease, diabetes, and life-style variables reco(r)ded similarly in CPRD GOLD and Aurum?
21/08/2020	Helicobacter pylori infection, its treatment and colorectal cancer risk: A two-phase study using treatment data from the UK Clinical Practice Database and serology information from the UK biobank
20/08/2020	Defining clinical research phenotypes using SNOMED CT
18/08/2020	To investigate trends in the occurrence of severe, food-induced allergic reactions
14/08/2020	Antibiotic treatment and major bleeding in anticoagulant medication users: analysis of health record data to support safer monitoring and prescribing
13/08/2020	Healthcare Resource Use, Baseline Characteristics, Clinical Outcomes and Survival Among Patients Undergoing SAVR vs TAVR in England
06/08/2020	Epidemiology, treatment patterns and healthcare resource use associated with prurigo nodularis in the UK: a retrospective analysis using the Clinical Practice Research Datalink
05/08/2020	Excess mortality during the COVID-19 pandemic
31/07/2020	Indirect acute effects of the COVID-19 pandemic on physical and psychological morbidity in the UK
30/07/2020	Using linked primary care and viral surveillance data to develop risk stratification models to inform management of severe COVID-19