Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
08/07/2020	Retrospective cohort study on first-time use of insulin detemir for diabetes type 2 glycaemic control in elderly and multimorbidity patients living in the United Kingdom
08/07/2020	Descriptive analysis of patterns of primary care demand in England during the COVID-19 pandemic
07/07/2020	Primary care service use towards end of life among patients who died before and during the COVID-19 epidemic: a nationwide cohort study using the Clinical Practice Research DataLink
06/07/2020	Understanding non-recovery after an exacerbation of chronic pulmonary obstructive disease
01/07/2020	Evaluation of the drivers in heterogeneity in unplanned hospital admissions and mortality in frail and multimorbidity elderly patients before and during/after COVID-19
29/06/2020	Selective Serotonin Reuptake Inhibitors and the Risk of Type 2 Diabetes Mellitus in Children and Youths
26/06/2020	A cohort study examining access to NHS weight management services using routine data from primary and secondary care
23/06/2020	Examining methodology to identify patterns of consulting in primary care for different groups of patients before a diagnosis of cancer: a matched retrospective cohort study
23/06/2020	The prevalent new-user design for cohort studies with no active comparator: The example of statins and cancer
23/06/2020	Risk of major adverse cardiac events in atherosclerotic cardiovascular disease, atherosclerotic cardiovascular disease - risk equivalent and familial hypercholesterolaemia patients with elevated low-density lipoprotein cholesterol
22/06/2020	Fluoroquinolones and the risk of retinal detachment, uveitis, peripheral neuropathy, and hospitalisation with aortic aneurysm or dissection
18/06/2020	Risk factors and outcomes of COVID-19 in individuals with Down syndrome
18/06/2020	Investigation into changes in Prostate Specific Antigen (PSA) testing rate over time: A join point analysis
17/06/2020	Area, maternal and child determinants of MMR uptake
17/06/2020	International trends in dual antiplatelet therapy among PCI-treated STEMI and NSTEMI patients: Pendant study in the UK
17/06/2020	Impact of suboptimal temperature exposure on health at all stages of care
16/06/2020	Evaluating the health impact of familial hypercholesterolaemia in primary care patients compared with an intensively managed specialist disease registry
16/06/2020	The Burden of Illness of Human Health Outcomes Arising from Human-Animal Interactions
12/06/2020	Assessing factors associated with the COVID-19 risk in people with asthma
09/06/2020	Risk factors for and long-term outcomes in people with covid-19 admitted to hospital in England