Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
28/02/2020	SELECT: Selection of Eligible People for Lung Cancer Screening using Electronic Primary Care DaTa: Validation of pre-existing prediction models
28/02/2020	Utilisation, effectiveness, and safety of direct oral anticoagulants in patients with non-valvular atrial fibrillation and liver disease
27/02/2020	Association of diabetes control on the risk of venous thrombosis: a nested case control study
27/02/2020	Ethnic Inequality in Diagnosis and Outcomes of Cancer
27/02/2020	Screening for diabetes and glucose intolerance disorders after gestational diabetes in primary care: A retrospective cohort analysis from the UK Clinical Practice Research Datalink (CPRD)
18/02/2020	A retrospective cohort study to assess whether urate lowering therapy improves outcomes in patients with hyperuricemia and/or gout with a history of heart failure
18/02/2020	Incidence of Sexually Transmitted Infections (STIs) in the UK Primary Care Setting
18/02/2020	Aclidinium Bromide PASS to Evaluate the Risk of Cardiovascular Endpoints: Stroke and Acute Myocardial Infarction
17/02/2020	Multimorbidity and clinical guidelines: using epidemiology to quantify the applicability of trial evidence to inform guideline development
13/02/2020	Determinants of treatment patterns of Parkinson’s Disease in the United Kingdom
10/02/2020	Incidence, prevalence, treatment patterns and health care resource use of women with vasomotor symptoms in the UK: A descriptive study using electronic medical records
10/02/2020	Time Trends in identification of Autism Spectrum Disorders
07/02/2020	Cardiovascular comorbidity prevalence in males with haemophilia A
31/01/2020	Incidence of venous thromboembolism following colorectal resectional surgery
31/01/2020	Epidemiology, outcomes, treatment patterns, and health resource utilization among English patients with peripheral artery disease (PAD) and with PAD related lower-extremity revascularization (PAD-LER)
31/01/2020	Predictors of cardiovascular event risk in a population with Atherosclerotic Cardiovascular Disease (ASCVD) or Heterozygous Familial Hypercholesterolemia (HeFH)
31/01/2020	Real World Effectiveness and Adverse Events Caused by ACE inhibitors and ARBs for Reduction in Cardiovascular Events
31/01/2020	Impact of EU label changes and revised pregnancy prevention programme for medicinal products containing valproate: utilisation and prescribing trends
30/01/2020	Impact of Covid-19 on primary care contact, referrals to follow-up care and patient outcomes after emergency department and primary care presentations for self-harm: cohort study using linked hospital and primary care health records
30/01/2020	Factors associated with progression of chronic kidney disease from stage 3 to 5 in patients with diabetes (PRIDE)